anti-CRISPR ID Family Type Status Source of species Comments Reference
anti_CRISPR0052AcrIIC1II-CVerifiedBrackiella oedipodisThis protein can inhibit the activity of one or more representative type II-C Cas9 orthologs 27984730
anti_CRISPR0054AcrIIC1II-CVerifiedNeisseria meningitidisThis protein can inhibit the activity of one or more representative type II-C Cas9 orthologs 27984730
anti_CRISPR0063AcrIIC2II-CVerifiedNeisseria meningitidisThis protein has robust anti-CRISPR II-C activity 27984730
anti_CRISPR0119AcrIIC3II-CVerifiedNeisseria meningitidisThis protein has robust anti-CRISPR II-C activity. This protein appear to be the most potent to inhibit editing of human genome 27984730
anti_CRISPR0134AcrIIA1II-AVerifiedListeria monocytogenes J0161This protein prevents Cas9 binding and gene editing in bacteria and human cells, including currently the most widely used Cas9 from Streptococcus pyogenes 28041849
anti_CRISPR0246AcrIIA2II-AVerifiedListeria monocytogenes J0161This protein prevents Cas9 binding and gene editing in bacteria and human cells, including currently the most widely used Cas9 from Streptococcus pyogenes 28041849
anti_CRISPR0338AcrIIA3II-AVerifiedListeria monocytogenes Lm_1880This protein prevents Cas9 binding and gene editing in bacteria and human cells, including currently the most widely used Cas9 from Streptococcus pyogenes 28041849
anti_CRISPR0384AcrIIA4II-AVerifiedListeria monocytogenes J0161This protein prevents Cas9 binding and gene editing in bacteria and human cells, including currently the most widely used Cas9 from Streptococcus pyogenes 28041849
anti_CRISPR0407AcrIE1I-EVerifiedPseudomonas phage JBD5The protein mediates inhibition of the P. aeruginosa SMC4386 type I-E system 24736222
anti_CRISPR0408AcrIE3I-EVerifiedPseudomonas phage DMS3The protein mediates inhibition of the P. aeruginosa SMC4386 type I-E system 24736222
anti_CRISPR0409AcrIE2I-EVerifiedPseudomonas phage JBD88aThe protein mediates inhibition of the P. aeruginosa SMC4386 type I-E system 24736222
anti_CRISPR0410AcrIE4I-EVerifiedPseudomonas phage D3112The protein mediates inhibition of the P. aeruginosa SMC4386 type I-E system 24736222
anti_CRISPR0430AcrVIBVI-BVerifiedBergeyella zoohelcum ATCC 43767Csx27, was identified as an inhibitor for both B. zoohelcum Cas13b (type VI-B1) and P. buccae Cas13b (type VI-B2) systems 28065598
anti_CRISPR0432AcrVIBVI-BVerifiedBergeyella zoohelcumCsx27, was identified as an inhibitor for both B. zoohelcum Cas13b (type VI-B1) and P. buccae Cas13b (type VI-B2) systems 28065598
anti_CRISPR0433AcrIIA5II-AVerifiedStreptococcus phage D4276An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9 28785032
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