anti_CRISPR0499 | AcrIF11 | I-F | Verified | Moraxella catarrhalis BC8 | -- |
30190308
|
anti_CRISPR0500 | AcrVA2 | V-A | Verified | Moraxella bovoculi | It inhibits Cas12a |
30190308
|
anti_CRISPR0501 | AcrVA3 | V-A,I-C | Verified | Moraxella caviae | It showed stronger Cas12a inhibition and also showed partial restoration of phage titer during type I-C targeting |
30190308
|
anti_CRISPR0553 | AcrIIC4 | II-C | Verified | Haemophilus parainfluenzae | Its expression completely inhibited the activity of HpaCas9 and decreased the activity of NmeCas9 by 100-fold |
30514786
|
anti_CRISPR0554 | AcrIIC5 | II-C | Verified | Simonsiella muelleri | Its expression completely inhibited the activity of both NmeCas9 and HpaCas9 |
30514786
|
anti_CRISPR0555 | AcrVA1 | V-A | Verified | Moraxella bovoculi | It inhibited DNA cleavage by all three Cas12a enzymes; the strongest inhibition was observed for MbCas12a, and the weakest was observed for AsCas12a. |
30190307
|
anti_CRISPR0556 | AcrVA4 | V-A | Verified | Moraxella bovoculi | It inhibited dsDNA cleavage for both MbCas12a and LbCas12a but did not inhibit AsCas12a. |
30190307
|
anti_CRISPR0557 | AcrVA5 | V-A | Verified | Moraxella bovoculi | It inhibited dsDNA cleavage for both MbCas12a and LbCas12a but did not inhibit AsCas12a. |
30190307
|
anti_CRISPR0558 | AcrIIA7 | II-A | Verified | metagenome | It inhibit SpCas9 activity in our in vitro DNA cleavage assay |
30737174
|
anti_CRISPR0559 | AcrIIA8 | II-A | Verified | metagenome | It inhibit SpCas9 activity in our in vitro DNA cleavage assay |
30737174
|
anti_CRISPR0560 | AcrIIA9 | II-A | Verified | metagenome | It inhibit SpCas9 activity in our in vitro DNA cleavage assay |
30737174
|
anti_CRISPR0561 | AcrIIA10 | II-A | Verified | metagenome | It inhibit SpCas9 activity in our in vitro DNA cleavage assay |
30737174
|
anti_CRISPR1284 | AcrIIA6 | II-A | Verified | Streptococcus phage D1811 | It from S. thermophilus phages inhibit Cas9-mediated genome editing of human cells |
30046034
|
anti_CRISPR1285 | AcrIIA6 | II-A | Verified | Streptococcus phage D1024 | It from S. thermophilus phages inhibit Cas9-mediated genome editing of human cells |
30046034
|
anti_CRISPR1286 | AcrIIA11 | II-A | Verified | Clostridiales | It inhibits SpyCas9 |
31502535
|