General information

Anti-CRISPR ID:anti_CRISPR0134
Accession:AEO04364.1
Anti-CRISPR type:II-A
Family:AcrIIA1
Organism:
Taxonomy:Bacteria;Firmicutes;Bacilli;Bacillales;Listeriaceae;Listeria
Uniprot entry:--
Uniprot entry name:--
Structure:5Y6A:
5Y69:
Inhibition stage:
Complexed with:
Interactor (DIP):--
Interactor (STRING):--
Protein sequence:MTIKLLDEFLKKHDLTRYQLSKLTGISQNTLKDQNEKPLNKYTVSILRSLSLISGLSVSDVLFELEDIEKNSDDLAGFKHLLDKYKLSFPAQEFELYCLIKEFESANIEVLPFTFNRFENEEHVNIKKDVCKALENAITVLKEKKNELL
Length of sequence:149
Verified:Verified
Comments:This protein prevents Cas9 binding and gene editing in bacteria and human cells, including currently the most widely used Cas9 from Streptococcus pyogenes
Pubmed: PMID:28041849
Rauch Benjamin J,Silvis Melanie R,Hultquist Judd F et al. Inhibition of CRISPR-Cas9 with Bacteriophage Proteins.[J] .Cell, 2017, 168: 150-158.e10.
Locus tag:LMOG_03146
Coding region:CP002001.1:2360593..2361042
Gene name:--
Gene ID:--
Gene Sequence:--