anti_CRISPR0495 | AcrVA1 | V-A | Verified | Moraxella bovoculi | It robustly inhibits Cas12a |
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anti_CRISPR0496 | AcrVA2 | V-A | Verified | Moraxella bovoculi | It robustly inhibits Cas12a |
30190308
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anti_CRISPR0497 | AcrVA3 | V-A | Verified | Moraxella bovoculi | It possessed subtle anti-Cas12a activity but was toxic to cells and adversely affected JBD30 phage growth independently of Cas12a |
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anti_CRISPR0500 | AcrVA2 | V-A | Verified | Moraxella bovoculi | It inhibits Cas12a |
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anti_CRISPR0501 | AcrVA3 | V-A,I-C | Verified | Moraxella caviae | It showed stronger Cas12a inhibition and also showed partial restoration of phage titer during type I-C targeting |
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anti_CRISPR0555 | AcrVA1 | V-A | Verified | Moraxella bovoculi | It inhibited DNA cleavage by all three Cas12a enzymes; the strongest inhibition was observed for MbCas12a, and the weakest was observed for AsCas12a. |
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anti_CRISPR0556 | AcrVA4 | V-A | Verified | Moraxella bovoculi | It inhibited dsDNA cleavage for both MbCas12a and LbCas12a but did not inhibit AsCas12a. |
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anti_CRISPR0557 | AcrVA5 | V-A | Verified | Moraxella bovoculi | It inhibited dsDNA cleavage for both MbCas12a and LbCas12a but did not inhibit AsCas12a. |
30190307
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anti_CRISPR3606 | AcrVA1 | V-A | Predict | Moraxella bovoculi | -- | -- |
anti_CRISPR3607 | AcrVA1 | V-A | Predict | Moraxella bovoculi | -- | -- |
anti_CRISPR3608 | AcrVA1 | V-A | Predict | Moraxella bovoculi | -- | -- |
anti_CRISPR3609 | AcrVA1 | V-A | Predict | Moraxella bovoculi | -- | -- |
anti_CRISPR3610 | AcrVA2 | V-A | Predict | Moraxella catarrhalis BC1 | -- | -- |
anti_CRISPR3611 | AcrVA2 | V-A | Predict | Moraxella catarrhalis BC1 | -- | -- |
anti_CRISPR3612 | AcrVA3 | V-A | Predict | Moraxella caviae | -- | -- |